Protests that originated in Minneapolis after a white police officer killed George Floyd, a 46-year-old black man, quickly spread around the country. The reality of social inequality create anger and despair that is now playing out on the streets of cities throughout the country.  How did we get here and what is the way forward?   What are specific health impacts on individual, family and communities from both physical and mental perspectives?  What are effective pathways to breakthroughs in enforcement and judicial policies and civic engagement?  How do we begin to transform our social contract to include those who have been dehumanized, commoditized and underrepresented?